The Longevity Buffet — Issue 04

Welcome to the London Longevity Newsletter 🗞️ Here goes Issue 04 of the Buffet 🍴

RESEARCH SPOTLIGHT / LONG READ 🧬

Rapamycin, Not Metformin, Mirrors Dietary Restriction-Driven Lifespan Extension in Vertebrates: A Meta-Analysis - Read Here

Senescence-resistant human mesenchymal progenitor cells counter aging in primates - More Here

Immunological Biomarkers of Aging - The immune system has always played a key-role in eliminating pathogens and auto-immune diseases but is now being recognised for its role in fighting off non-communicable diseases associated with ageing, like cancer

How the UK Biobank was built - A great interview of someone who has been a key figure in building the Biobank over the last 20 years, with some lessons on founding an institution that won’t pay off for decades

The UN recently released a report highlighting the biology of ageing

MARKET MOMENTUM 💸

Parallel Bio raises $21M to create an alternative for animal models; See also - the secret fastback for animal drugs

Biotech financing: divide and reset — a comprehensive new report on the biotech funding landscape

ALPHA (the edge of having unique insights *earlier* than others/the market to drive asymmetric returns) 👀

A deep-dive on brain-computer interfaces

LONDON ECOSYSTEM HIGHLIGHTS 🌃

HUGE Highlight 🥳 🎉 London Longevity recently hosted the first AI for Longevity Hackathon, and we’re still buzzing with the energy from that event. Check out some LinkedIn posts to see what went down! Huge thanks to everyone who made it possible🤖🧬

Cambridge-based startup Shift Bioscience identifies novel single-gene target for safer cellular rejuvenation therapeutics 🎉

The UK Government launches OpenBind, an effort to create the largest open dataset of drug-protein interactions in history 🤖🧬

Late night cafe @ IDEA London for builders, happening later tonight (20th June 2025) 🧑‍💻👩‍💻

Longevity Summit Dublin 2025 due to happen soon, from 2-4 July 2025, with a great line-up of speakers 🧑‍💻👩‍💻

That's a wrap for Issue 04!

Let us know what you what you would like to see/hear more of from this newsletter. Reply to this email or leave a comment on Substack!

See you again in a couple weeks,

Prasasya from London Longevity

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