Welcome to the inaugural post of my 'Health 3.0 - Longevity Basics' series. Periodically, I'll offer actionable and practical guidance on aligning our daily routines with the principles of longevity and optimal health, grounded in current scientific understanding.

Today, we delve into the vast realm of supplements. While the world of supplements can be overwhelming, a new category has recently emerged, specifically targeting longevity. There isn’t one magic anti-aging compound (or even several), but a limited but growing number of studies suggest that certain supplements might help to “reverse” epigenetic aging, or preserve the 12 biological processes associated with aging, referred to as the 12 Hallmarks of Aging. 

In this article, I'll share insights I gathered from looking at recommendations by industry leaders and experts in longevity and functional health. Additionally, I'll delve into the science backing these 'longevity supplements' – ones that I personally incorporate into my daily routine. I hope you find this helpful.

The Players

Since people have been practicing medicine, the holy grail for human health has been to slow or stop aging. So it probably comes as no surprise that influential players in the health space have shared recommendations on the longevity supplements I’ll explore below.

The Longevity Experts

• David Sinclair, Ph.D., is a professor of genetics at Harvard University, where he studies why we age and how to slow its effects, and the author of Lifespan: Why We Age, and Why We Don’t Have To. He is also the founder of several biotech companies, including longevity startup Tally Health.

• Peter Attia, M.D., is a former surgeon who studied cancer therapies at the National Institutes of Health before launching Early Medical, a medical practice with the goal of lengthening patients’ lifespan and improving their healthspan. He’s the author of Outlive: The Science and Art of Longevity.

• Rhonda Patrick, Ph.D., is a biomedical researcher and educator who has studied aging, cancer, and nutrition—in particular, supplementation and aging. She is the CEO and co-founder of the longevity website FoundMyFitness.

• Mark Hyman, M.D., is the founder and director of The UltraWellness Center and the founder of the Cleveland Clinic’s Center for Functional Medicine. He has written several books on nutrition and longevity, including Young Forever: The Secrets to Living Your Longest, Healthiest Life.

• Bryan Johnson is an entrepreneur, venture capitalist, author, and the founder and CEO of

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